Lane Johnson OUT for Eagles vs. 49ers Playoff Game: Full Inactives List & Analysis (2026)

In a shocking turn of events, the Philadelphia Eagles will face the San Francisco 49ers in their Wild Card playoff game without their star right tackle, Lane Johnson. Despite earlier reports suggesting he would play, Johnson’s absence has sent ripples through the fanbase, leaving many to wonder how the offensive line will hold up. But here’s where it gets interesting: the 49ers boast the NFL’s weakest pass rush, ranking dead last in sacks. So, while Fred Johnson steps in as the starter, the matchup might not be as dire as it seems—though there’s no denying Lane Johnson’s irreplaceable skill. And this is the part most people miss: rookie Cameron Williams is active, adding unexpected depth to the tackle position. Could this be a blessing in disguise, or will the Eagles feel the weight of Johnson’s absence? Controversially, some argue that the 49ers’ weak pass rush downplays the impact of Lane Johnson’s absence—what do you think?

The Eagles’ inactive list also includes Brett Toth, Jakorian Bennett, Joshua Uche, Ty Robinson, A.J. Dillon, and Sam Howell. Toth, still recovering from a concussion, leaves Drew Kendall as the backup center and Matt Pryor as the primary guard backup. Bennett, a healthy scratch after a rough Week 18 performance, is benched in favor of rookie Mac McWilliams—a surprising shift. Uche, Robinson, and Dillon return to the sidelines as healthy scratches, while Howell remains the emergency third quarterback. Meanwhile, Andre Sam and Charley Hughlett are active after being elevated from the practice squad.

On the 49ers’ side, starting left tackle Trent Williams is active despite being questionable, a huge relief for their offense. However, starting wide receiver Ricky Pearsall and linebacker Dee Winters are inactive, as expected, after missing practice all week. Joining them on the sidelines are Luke Gifford, Isaac Guerendo, Chase Lucas, Jordan Watkins, and Kevin Givens.

But here’s the real question: With Lane Johnson out and the 49ers’ pass rush struggling, does this matchup favor the Eagles more than we think? Or will the absence of key players on both sides level the playing field? Share your thoughts below—this game is shaping up to be a fascinating battle of adjustments and strategy!

Lane Johnson OUT for Eagles vs. 49ers Playoff Game: Full Inactives List & Analysis (2026)

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